Camptothecin multifunctional nanoparticles effectively achieve a balance between the efficacy of breast cancer treatment and the preservation of intestinal homeostasis

Camptothecin multifunctional nanoparticles effectively achieve a balance between the efficacy of breast cancer treatment and the preservation of intestinal homeostasis

Camptothecin (CPT) exhibits potent antitumor activity; however, its clinical application is limited by significant gastrointestinal adverse effects (GAEs). Although the severity of GAEs associated with CPT derivatives has decreased, the incidence rate of these adverse effects has remained high. CPT...

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Bibliographic Details
Main Authors: Qingya Liu, Yun Yang, Meng Pan, Kun Shi, Dong Mo, Yicong Li, Meng Wang, Linfeng Guo, Zhiyong Qian
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-11-01
Series:Bioactive Materials
Subjects:
Camptothecin
PCRHNs
Intestinal barrier
Intestinal microbiota
Probiotics
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24003153

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http://www.sciencedirect.com/science/article/pii/S2452199X24003153

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