Efficacy and tolerability of brivaracetam monotherapy in childhood and juvenile absence epilepsy: An innovative adaptive trial design

Efficacy and tolerability of brivaracetam monotherapy in childhood and juvenile absence epilepsy: An innovative adaptive trial design

Abstract Objective Despite introduction of several antiseizure medications over the past two decades, treatment options for childhood absence epilepsy (CAE) and juvenile absence epilepsy (JAE) remain limited. We report the innovative adaptive design of an ongoing phase 2/3 trial to evaluate efficacy...

Full description

Bibliographic Details
Main Authors: Thomas Bast, Anne‐Liv Schulz, Florin Floricel, Diego Morita, Jody M. Cleveland, Jan‐Peer Elshoff
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Epilepsia Open
Subjects:
antiseizure medication
double‐blind placebo‐controlled
electroencephalogram
randomized withdrawal
seizures
Online Access:https://doi.org/10.1002/epi4.12628

Internet

https://doi.org/10.1002/epi4.12628

Similar Items