CRISPR-powered quantitative keyword search engine in DNA data storage
Abstract Despite the growing interest of archiving information in synthetic DNA to confront data explosion, quantitatively querying the data stored in DNA is still a challenge. Herein, we present Search Enabled by Enzymatic Keyword Recognition (SEEKER), which utilizes CRISPR-Cas12a to rapidly genera...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-46767-x |