Synthesis, molecular modeling and anticancer activity of new coumarin containing compounds

A series of new coumarin containing compounds were synthesized from 4-bromomethylcoumarin derivatives 2a, b and different heteroaromatic systems 4a-e, 6a-d, 8, 10 via methylene thiolinker. Twenty-four compounds were screened biologically against two human tumor cell lines, breast carcinoma MCF-7 and...

Full description

Bibliographic Details
Main Authors: Shaimaa A. Morsy, Abdelbasset A. Farahat, Magda N.A. Nasr, Atif S. Tantawy
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Saudi Pharmaceutical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016417300257