A genetic model for in vivo proximity labelling of the mammalian secretome

A genetic model for in vivo proximity labelling of the mammalian secretome

Organ functions are highly specialized and interdependent. Secreted factors regulate organ development and mediate homeostasis through serum trafficking and inter-organ communication. Enzyme-catalysed proximity labelling enables the identification of proteins within a specific cellular compartment....

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Bibliographic Details
Main Authors: Rui Yang, Amanda S. Meyer, Ilia A. Droujinine, Namrata D. Udeshi, Yanhui Hu, Jinjin Guo, Jill A. McMahon, Dominique K. Carey, Charles Xu, Qiao Fang, Jihui Sha, Shishang Qin, David Rocco, James Wohlschlegel, Alice Y. Ting, Steven A. Carr, Norbert Perrimon, Andrew P. McMahon
Format: Article
Language:English
Published: The Royal Society 2022-08-01
Series:Open Biology
Subjects:
proximity-labelling
BirA
TurboID
secretome
inter-organ communication
serum proteins
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.220149

Internet

https://royalsocietypublishing.org/doi/10.1098/rsob.220149

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