Differential Effects of an Alpha-2 Agonist on Wakefulness and Paradoxical Sleep in The Rat: A Polygraphic and Biochemical Approach

The purpose of this experiment was to determine the sensitivity of wakefulness and paradoxical sleep to the α2-agonist, c1onidine. The drug inhibited both wakefulness and paradoxical sleep but the smallest dose necessary to inhibit wakefulness was 64 times larger than the smallest dose inhibiting pa...

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Detalhes bibliográficos
Principais autores: Z. de Saint Hilaire, F. Karege, J.-M. Gaillard, R. Blois
Formato: Artigo
Idioma:English
Publicado em: Wiley 1997-01-01
coleção:Behavioural Neurology
Acesso em linha:http://dx.doi.org/10.3233/BEN-1997-102-307