Case Report: Successful engraftment of allogeneic hematopoietic stem cells using CAR-T cell therapy as the conditioning regimen in R/R Ph+ B cell acute lymphoblastic leukemia

Case Report: Successful engraftment of allogeneic hematopoietic stem cells using CAR-T cell therapy as the conditioning regimen in R/R Ph+ B cell acute lymphoblastic leukemia

BackgroundConsolidative allogeneic hematopoietic stem cells (allo-HSCs) after chimeric antigen receptor T cells (CAR-T) therapy is an emerging modality in hematologic malignancies. Knowledge about the success of allogeneic hematopoietic stem cell transplantation (allo-HSCT) after CAR-T therapy witho...

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Bibliographic Details
Main Authors: Lu Han, Ran Zhao, Jingyi Yang, Yingling Zu, Yanyan Liu, Jian Zhou, Linlin Li, Zhenghua Huang, Jishuai Zhang, Quanli Gao, Yongping Song, Keshu Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
B-cell acute lymphoblastic leukemia
CAR-T
allogeneic hematopoietic stem cell transplantation
conditioning regimen
CD19
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.965932/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.965932/full

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