Actions of Retinoic Acid in the Pathophysiology of HIV Infection

The vitamin A metabolite all-trans retinoic acid (RA) plays a key role in tissue homeostasis and mucosal immunity. RA is produced by gut-associated dendritic cells, which are among the first cells encountered by HIV. Acute HIV infection results in rapid reduction of RA levels and dysregulation of im...

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Bibliographic Details
Main Authors: Neil Sidell, Maureen A. Kane
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/14/8/1611