Premature senescence in primary muscle cultures of myotonic dystrophy type 2 is not associated with p16 induction

Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are multisystemic disorders linked to two different genetic loci and characterized by several features including myotonia, muscle weakness and atrophy, cardiac dysfunctions, cataracts and insulin-resistance. In both forms, expanded nucleotide sequence...

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Bibliographic Details
Main Authors: L.V. Renna, R. Cardani, A. Botta, G. Rossi, B. Fossati, E. Costa, G. Meola
Format: Article
Language:English
Published: PAGEPress Publications 2014-10-01
Series:European Journal of Histochemistry
Subjects:
Online Access:http://www.ejh.it/index.php/ejh/article/view/2444