Curcumin as a Modulator of P-Glycoprotein in Cancer: Challenges and Perspectives

Multidrug resistance (MDR) presents a serious challenge to the efficiency of cancer treatment, and may be associated with the overexpression of drug efflux pumps. P-glycoprotein (P-gp) is a drug efflux pump often found overexpressed in cases of acquired MDR. Nevertheless, there are no P-gp inhibitor...

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Bibliographic Details
Main Authors: Vanessa Lopes-Rodrigues, Emília Sousa, M. Helena Vasconcelos
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/9/4/71