Comparison of the pathological outcome and disease progression of two Mycobacterium caprae experimental challenge models in goats: endobronchial inoculation vs. intranasal nebulization

Comparison of the pathological outcome and disease progression of two Mycobacterium caprae experimental challenge models in goats: endobronchial inoculation vs. intranasal nebulization

BackgroundGoats are natural hosts of tuberculosis (TB) and are a valid animal model to test new vaccines and treatments to control this disease. In this study, a new experimental model of TB in goats based on the intranasal nebulization of Mycobacterium caprae was assessed in comparison with the end...

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Bibliographic Details
Main Authors: Cristian Melgarejo, Alex Cobos, Carles Planas, Jaume Fondevila, Maite Martín, Zoraida Cervera, Guillermo Cantero, Xavier Moll, Yvonne Espada, Mariano Domingo, Enric Vidal, Bernat Pérez de Val
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Microbiology
Subjects:
tuberculosis
Mycobacterium caprae
goat
experimental infection
intranasal
endobronchial
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1236834/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1236834/full

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