Cortical pain induced by optogenetic cortical spreading depression: from whole brain activity mapping

Highlights 1. We established an optogenetic mouse CSD model without irritation dura, which could mimic the behaviors of headache and photophobia. 2. It was the first time to depict a broad, unbiased neuronal activity map throughout the mouse brain after CSD. 3. Results of whole brain image and immun...

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Bibliographic Details
Main Authors: Chenghui Pi, Wenjing Tang, Zhishuai Li, Yang Liu, Qi Jing, Wei Dai, Tao Wang, Chunxiao Yang, Shengyuan Yu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-022-00985-w