Novel Combination Strategies to Enhance Immune Checkpoint Inhibition in Cancer Immunotherapy: A Narrative Review

Programmed cell death protein-1 (PD-1) is an immune checkpoint receptor that induces and maintains tolerance of T cells, invariant natural killer T (iNKT) cells, and natural killer (NK) cells, among other lymphocytes. Immune checkpoint inhibition by PD-1 blockade restores the lymphocytic immunostim...

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Bibliographic Details
Main Authors: Jonathan A. Hermel, Cassi M. Bruni, Darren S. Sigal
Format: Article
Language:English
Published: University Library System, University of Pittsburgh 2020-12-01
Series:International Journal of Medical Students
Subjects:
Online Access:https://ijms.info/IJMS/article/view/753