90-gene signature assay for tissue origin diagnosis of brain metastases

90-gene signature assay for tissue origin diagnosis of brain metastases

Abstract Background Brain metastases (BM) are the most common intracranial tumors. 2–14% of BM patients present with unknown primary site despite intensive evaluations. This study aims to evaluate the performance of a 90-gene expression signature in determining the primary sites for BM samples. Meth...

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Bibliographic Details
Main Authors: Yulong Zheng, Yongfeng Ding, Qifeng Wang, Yifeng Sun, Xiaodong Teng, Qiqi Gao, Weixiang Zhong, Xiaofeng Lou, Cheng Xiao, Chengshu Chen, Qinghua Xu, Nong Xu
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Translational Medicine
Subjects:
Primary brain tumor
Brain metastases
Gene expression profiling
Tumor origin identification
Quantitative real-time PCR
Online Access:http://link.springer.com/article/10.1186/s12967-019-2082-1

Internet

http://link.springer.com/article/10.1186/s12967-019-2082-1

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