Structural insights into the functional diversity of the CDK–cyclin family

Since their characterization as conserved modules that regulate progression through the eukaryotic cell cycle, cyclin-dependent protein kinases (CDKs) in higher eukaryotic cells are now also emerging as significant regulators of transcription, metabolism and cell differentiation. The cyclins, though...

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Bibliographic Details
Main Authors: Daniel J. Wood, Jane A. Endicott
Format: Article
Language:English
Published: The Royal Society 2018-09-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.180112