Intraperitoneally Administered Vancomycin in Patients with Peritoneal Dialysis-Associated Peritonitis: Population Pharmacokinetics and Dosing Implications

Intraperitoneally Administered Vancomycin in Patients with Peritoneal Dialysis-Associated Peritonitis: Population Pharmacokinetics and Dosing Implications

Peritonitis is a limiting complication of peritoneal dialysis, which is treated by intraperitoneal administration of antibiotics. Various dosing strategies are recommended for intraperitoneally administered vancomycin, which leads to large differences in intraperitoneal vancomycin exposure. Based on...

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Bibliographic Details
Main Authors: Jan Miroslav Hartinger, Danica Michaličková, Eliška Dvořáčková, Karolína Hronová, Elke H. J. Krekels, Barbora Szonowská, Vladimíra Bednářová, Hana Benáková, Gabriela Kroneislová, Jan Závora, Vladimír Tesař, Ondřej Slanař
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceutics
Subjects:
glycopeptides
therapeutic drug monitoring
methicillin resistant <i>Staphylococcus aureus</i> (MRSA)
area under the curve (AUC)
drug-exposure
renal replacement therapy
Online Access:https://www.mdpi.com/1999-4923/15/5/1394

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https://www.mdpi.com/1999-4923/15/5/1394

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