Function of the CRISPR-Cas System of the Human Pathogen <named-content content-type="genus-species">Clostridium difficile</named-content>

ABSTRACT Clostridium difficile is the cause of most frequently occurring nosocomial diarrhea worldwide. As an enteropathogen, C. difficile must be exposed to multiple exogenous genetic elements in bacteriophage-rich gut communities. CRISPR (clustered regularly interspaced short palindromic repeats)-...

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Main Authors: Pierre Boudry, Ekaterina Semenova, Marc Monot, Kirill A. Datsenko, Anna Lopatina, Ognjen Sekulovic, Maicol Ospina-Bedoya, Louis-Charles Fortier, Konstantin Severinov, Bruno Dupuy, Olga Soutourina
Format: Article
Language:English
Published: American Society for Microbiology 2015-10-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01112-15