Molecular Analysis of Biliary Tract Cancers with the Custom 3′ RACE-Based NGS Panel

Molecular Analysis of Biliary Tract Cancers with the Custom 3′ RACE-Based NGS Panel

The technique 3’ rapid amplification of cDNA ends (3′ RACE) allows for detection of translocations with unknown gene partners located at the 3′ end of the chimeric transcript. We composed a 3′ RACE-based RNA sequencing panel for the analysis of <i>FGFR1–4</i> gene rearrangements, detecti...

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Bibliographic Details
Main Authors: Natalia V. Mitiushkina, Vladislav I. Tiurin, Aleksandra A. Anuskina, Natalia A. Bordovskaya, Anna D. Shestakova, Aleksandr S. Martianov, Mikhail G. Bubnov, Anna S. Shishkina, Maria V. Semina, Aleksandr A. Romanko, Ekaterina S. Kuligina, Evgeny N. Imyanitov
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Diagnostics
Subjects:
biliary tract cancer
cholangiocarcinoma
targeted RNA sequencing
3′ RACE
<i>FGFR2</i> translocation
NGS library preparation
Online Access:https://www.mdpi.com/2075-4418/13/20/3168

Internet

https://www.mdpi.com/2075-4418/13/20/3168

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