Thermosensitive Intravitreal In Situ Implant of Cefuroxime Based on Poloxamer 407 and Hyaluronic Acid

Thermosensitive Intravitreal In Situ Implant of Cefuroxime Based on Poloxamer 407 and Hyaluronic Acid

The main method of treatment and prevention of endophthalmitis is a combination of intravitreal and topical administration of antibiotics, such as cefuroxime moxifloxacin or vancomycin. However, this method is ineffective due to the rapid elimination of the drug. This problem can be solved with the...

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Bibliographic Details
Main Authors: Elena O. Bakhrushina, Anastasia I. Dubova, Maria S. Nikonenko, Viktoriya V. Grikh, Marina M. Shumkova, Tatyana V. Korochkina, Ivan I. Krasnyuk
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Gels
Subjects:
in situ implant
intravitreal injection
cefuroxime
endophthalmitis
poloxamers
solid dispersion
Online Access:https://www.mdpi.com/2310-2861/9/9/693

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https://www.mdpi.com/2310-2861/9/9/693

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