Proteomics reveals a new DNA repair factor involved in DNA damage signaling

Stalling of the DNA replication machinery activates the ATR checkpoint kinase, which coordinates the cellular responses to replication stress. New studies identify a novel ATR activator, ETAA1, which is indispensable for the maintenance of genome integrity. Dysregulation of ETAA1 may contribute to t...

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Bibliographic Details
Main Author: Markus Räschle
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2016.1263713