Quantifying intracellular trafficking of silica-coated magnetic nanoparticles in live single cells by site-specific direct stochastic optical reconstruction microscopy

Abstract Background Nanoparticles have been used for biomedical applications, including drug delivery, diagnosis, and imaging based on their unique properties derived from small size and large surface-to-volume ratio. However, concerns regarding unexpected toxicity due to the localization of nanopar...

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Bibliographic Details
Main Authors: Suresh Kumar Chakkarapani, Tae Hwan Shin, Seungah Lee, Kyung-Soo Park, Gwang Lee, Seong Ho Kang
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-021-01147-1