Associations between polygenic risk of coronary artery disease and type 2 diabetes, lifestyle, and cardiovascular mortality: A prospective UK Biobank study

Associations between polygenic risk of coronary artery disease and type 2 diabetes, lifestyle, and cardiovascular mortality: A prospective UK Biobank study

BackgroundPrevious studies primarily targeted the ability of polygenic risk scores (PRSs) to predict a specific disease, and only a few studies have investigated the association between genetic risk scores and cardiovascular (CV) mortality. We assessed PRSs for coronary artery disease (CAD) and type...

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Bibliographic Details
Main Authors: Jae-Seung Yun, Sang-Hyuk Jung, Manu Shivakumar, Brenda Xiao, Amit V. Khera, Woong-Yang Park, Hong-Hee Won, Dokyoon Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
polygenic risk score
lifestyle
cardiovascular mortality
coronary artery disease
type 2 diabetes mellitus
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.919374/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.919374/full

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