Functional MAPT haplotypes: Bridging the gap between genotype and neuropathology

The microtubule-associated protein tau (MAPT) locus has long been associated with sporadic neurodegenerative disease, notably progressive supranuclear palsy and corticobasal degeneration, and more recently with Alzheimer’s disease and Parkinson’s disease. However, the functional biological mechanism...

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Bibliographic Details
Main Authors: Tara M. Caffrey, Richard Wade-Martins
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107000940