Functional MAPT haplotypes: Bridging the gap between genotype and neuropathology
The microtubule-associated protein tau (MAPT) locus has long been associated with sporadic neurodegenerative disease, notably progressive supranuclear palsy and corticobasal degeneration, and more recently with Alzheimer’s disease and Parkinson’s disease. However, the functional biological mechanism...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-07-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996107000940 |