Effect of Blood Flow on Cardiac Morphogenesis and Formation of Congenital Heart Defects

Effect of Blood Flow on Cardiac Morphogenesis and Formation of Congenital Heart Defects

Congenital heart disease (CHD) affects about 1 in 100 newborns and its causes are multifactorial. In the embryo, blood flow within the heart and vasculature is essential for proper heart development, with abnormal blood flow leading to CHD. Here, we discuss how blood flow (hemodynamics) affects hear...

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Bibliographic Details
Main Authors: Fernando Trinidad, Floyd Rubonal, Ignacio Rodriguez de Castro, Ida Pirzadeh, Rabin Gerrah, Arash Kheradvar, Sandra Rugonyi
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
cardiac hemodynamics
heart development
mechanotransduction
biofluid mechanics
congenital heart disease
Online Access:https://www.mdpi.com/2308-3425/9/9/303

Internet

https://www.mdpi.com/2308-3425/9/9/303

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