The role of macrophages in right ventricular remodeling in experimental pulmonary hypertension

The role of macrophages in right ventricular remodeling in experimental pulmonary hypertension

Abstract Right ventricular (RV) failure is the primary cause of death in pulmonary hypertension (PH), but the mechanisms of RV failure are not well understood. We hypothesized macrophages in the RV contribute to the RV response in PH. We induced PH in mice with hypoxia (FiO2 10%) and Schistosoma man...

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Bibliographic Details
Main Authors: Sue Gu, Claudia Mickael, Rahul Kumar, Michael H. Lee, Linda Sanders, Biruk Kassa, Julie Harral, Jason Williams, Kirk C. Hansen, Kurt R. Stenmark, Rubin M. Tuder, Brian B. Graham
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Pulmonary Circulation
Subjects:
adaptation
hypoxia
inflammation
right heart
Schistosoma
Online Access:https://doi.org/10.1002/pul2.12105

Internet

https://doi.org/10.1002/pul2.12105

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