A single crossing-over event in voltage-sensitive Na+ channel genes may cause critical failure of dengue mosquito control by insecticides.

The voltage-sensitive sodium (Na+) channel (Vssc) is the target site of pyrethroid insecticides. Pest insects develop resistance to this class of insecticide by acquisition of one or multiple amino acid substitution(s) in this channel. In Southeast Asia, two major Vssc types confer pyrethroid resist...

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Bibliographic Details
Main Authors: Koichi Hirata, Osamu Komagata, Kentaro Itokawa, Atsushi Yamamoto, Takashi Tomita, Shinji Kasai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4148226?pdf=render