Cyclodextrins and Their Polymers Affect the Lipid Membrane Permeability and Increase Levofloxacin’s Antibacterial Activity In Vitro

Cyclodextrins and Their Polymers Affect the Lipid Membrane Permeability and Increase Levofloxacin’s Antibacterial Activity In Vitro

Cyclodextrins (CDs) are promising drug carriers that are used in medicine. We chose CDs with different substituents (polar/apolar, charged/neutral) to obtain polymers (CDpols) with different properties. CDpols are urethanes with average Mw of ~120 kDa; they form nanoparticles 100–150 nm in diameter...

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Bibliographic Details
Main Authors: Anna A. Skuredina, Anastasia S. Tychinina, Irina M. Le-Deygen, Sergey A. Golyshev, Tatiana Yu. Kopnova, Nikolay T. Le, Natalya G. Belogurova, Elena V. Kudryashova
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Polymers
Subjects:
cyclodextrin
levofloxacin
liposome
spectroscopy
antibacterial activity
Online Access:https://www.mdpi.com/2073-4360/14/21/4476

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https://www.mdpi.com/2073-4360/14/21/4476

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