Human immunodeficiency virus type 1 Vpr: oligomerization is an essential feature for its incorporation into virus particles

<p>Abstract</p> <p>HIV-1 Vpr, a nonstructural viral protein associated with virus particles, has a positive role in the efficient transport of PIC into the nucleus of non-dividing target cells and enhances virus replication in primary T cells. Vpr is a 96 amino acid protein and the...

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Bibliographic Details
Main Authors: Klein-Seetharaman Judith, Srinivasan Alagarsamy, Yanamala Naveena, Li Yaming, Dempsey Timothy M, Le Thien, Tastan Oznur, Walker Leah A, Venkatachari Narasimhan J, Montelaro Ronald C, Ayyavoo Velpandi
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/7/1/119