Nonhuman Primates Are Protected against Marburg Virus Disease by Vaccination with a Vesicular Stomatitis Virus Vector-Based Vaccine Prepared under Conditions to Allow Advancement to Human Clinical Trials

Nonhuman Primates Are Protected against Marburg Virus Disease by Vaccination with a Vesicular Stomatitis Virus Vector-Based Vaccine Prepared under Conditions to Allow Advancement to Human Clinical Trials

Vaccines are needed to disrupt or prevent continued outbreaks of filoviruses in humans across Western and Central Africa, including outbreaks of Marburg virus (MARV). As part of a filovirus vaccine product development plan, it is important to investigate dose response early in preclinical developmen...

Full description

Bibliographic Details
Main Authors: Christopher L. Cooper, Gavin Morrow, Maoli Yuan, John W. Coleman, Fuxiang Hou, Lucia Reiserova, Shui L. Li, Denise Wagner, Alexei Carpov, Olivia Wallace-Selman, Kristie Valentin, Yesle Choi, Aaron Wilson, Andrew Kilianski, Eddy Sayeed, Krystle N. Agans, Viktoriya Borisevich, Robert W. Cross, Thomas W. Geisbert, Mark B. Feinberg, Swati B. Gupta, Christopher L. Parks
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Vaccines
Subjects:
vesicular stomatitis virus
vaccine vector
Marburg virus vaccine
emerging infectious disease
filoviruses
Online Access:https://www.mdpi.com/2076-393X/10/10/1582

Internet

https://www.mdpi.com/2076-393X/10/10/1582

Similar Items