Neuroprotection afforded by targeting G protein-coupled receptors in heteromers and by heteromer-selective drugs

G protein-coupled receptors (GPCRs) are the target of hundreds of approved drugs. Although these drugs were designed to target individual receptors, it is becoming increasingly apparent that GPCRs interact with each other to form heteromers. Approved drug targets are often part of a GPCR heteromer,...

Full description

Bibliographic Details
Main Authors: Rafael Franco, Gemma Navarro
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1222158/full