Knockdown of Antisense Noncoding Mitochondrial RNA Reduces Tumorigenicity of Patient-Derived Clear Cell Renal Carcinoma Cells in an Orthotopic Xenograft Mouse Model

Knockdown of Antisense Noncoding Mitochondrial RNA Reduces Tumorigenicity of Patient-Derived Clear Cell Renal Carcinoma Cells in an Orthotopic Xenograft Mouse Model

Clear cell renal cell carcinoma (ccRCC) is the most prevalent form of renal cancer and its treatment is hindered by a resistance to targeted therapies, immunotherapies and combinations of both. We have reported that the knockdown of the antisense noncoding mitochondrial RNAs (ASncmtRNAs) with chemic...

Full description

Bibliographic Details
Main Authors: Mariela Araya, Francisca Sepúlveda, Jaime Villegas, Luis Alarcón, Luis O. Burzio, Verónica A. Burzio, Vincenzo Borgna
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
clear cell renal cell carcinoma
non-coding RNA
cancer therapy
orthotopic mouse renal model
patient-derived primary cultures
Online Access:https://www.mdpi.com/2072-6694/16/4/830

Internet

https://www.mdpi.com/2072-6694/16/4/830

Similar Items