High-resolution global peptide-protein docking using fragments-based PIPER-FlexPepDock.

Peptide-protein interactions contribute a significant fraction of the protein-protein interactome. Accurate modeling of these interactions is challenging due to the vast conformational space associated with interactions of highly flexible peptides with large receptor surfaces. To address this challe...

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Bibliographic Details
Main Authors: Nawsad Alam, Oriel Goldstein, Bing Xia, Kathryn A Porter, Dima Kozakov, Ora Schueler-Furman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1005905