Impaired neutralizing antibodies and preserved cellular immunogenicity against SARS-CoV-2 in systemic autoimmune rheumatic diseases

Impaired neutralizing antibodies and preserved cellular immunogenicity against SARS-CoV-2 in systemic autoimmune rheumatic diseases

Abstract Reports on vaccine immunogenicity in patients with systemic autoimmune rheumatic diseases (SARDs) have been inconclusive. Here, we report the immunogenicity of heterologous prime-boost with an inactivated vaccine followed by an adenoviral vector vaccine in patients with SARDs using anti-RBD...

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Bibliographic Details
Main Authors: Porntip Intapiboon, Parichat Uae-areewongsa, Jomkwan Ongarj, Ratchanon Sophonmanee, Purilap Seepathomnarong, Bunya Seeyankem, Smonrapat Surasombatpattana, Nawamin Pinpathomrat
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-022-00568-9

Internet

https://doi.org/10.1038/s41541-022-00568-9

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