TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1

TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1

Abstract Background T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is a cell surface molecule that was first discovered on T cells. However, recent studies revealed that it is also highly expressed in acute myeloid leukemia (AML) cells and it is related to AML progression. As, Glutamine...

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Bibliographic Details
Main Authors: Hooriyeh Shapourian, Mustafa Ghanadian, Nahid Eskandari, Abolfazl Shokouhi, Gülderen Yanikkaya Demirel, Alexandr V. Bazhin, Mazdak Ganjalikhani-Hakemi
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Cancer
Subjects:
Acute myeloid leukemia (AML)
T cell immunoglobulin and mucin-domain containing-3 (TIM-3)
Galectin-9 (Gal-9)
Glutamine metabolism
Glutaminase (GLS)
Glutamate dehydrogenase (GDH)
Online Access:https://doi.org/10.1186/s12885-024-11898-3

Internet

https://doi.org/10.1186/s12885-024-11898-3

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