Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells

Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells

Abstract Background Adoptive immunotherapy is gaining momentum to fight malignancies, whereby γδ T cells have received recent attention as an alternative cell source as to natural killer cells and αβ T cells. The advent of γδ T cells is largely due to their ability to recognize and target tumor cell...

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Bibliographic Details
Main Authors: Heleen H. Van Acker, Sébastien Anguille, Yannick Willemen, Johan M. Van den Bergh, Zwi N. Berneman, Eva Lion, Evelien L. Smits, Viggo F. Van Tendeloo
Format: Article
Language:English
Published: BMC 2016-09-01
Series:Journal of Hematology & Oncology
Subjects:
Adoptive transfer
Expansion protocol
Gamma delta T cells
Interleukin-15
Leukemia
Online Access:http://link.springer.com/article/10.1186/s13045-016-0329-3

Internet

http://link.springer.com/article/10.1186/s13045-016-0329-3

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