Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies

Genomic instability plays a crucial role in oncogenesis. Somatically acquired mutations can disable some genes and inappropriately activate others. In addition, chromosomal rearrangements can amplify, delete, or even fuse genes, altering their functions and contributing to malignant phenotypes. Usin...

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Detalles Bibliográficos
Autores principales: J. Kimble Frazer, Lance A. Batchelor, Diana F. Bradley, Kim H. Brown, Kimberly P. Dobrinski, Charles Lee, Nikolaus S. Trede
Formato: Artículo
Lenguaje:English
Publicado: Wiley 2012-01-01
Colección:Advances in Hematology
Acceso en línea:http://dx.doi.org/10.1155/2012/627920