Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies
Genomic instability plays a crucial role in oncogenesis. Somatically acquired mutations can disable some genes and inappropriately activate others. In addition, chromosomal rearrangements can amplify, delete, or even fuse genes, altering their functions and contributing to malignant phenotypes. Usin...
Autores principales: | , , , , , , |
---|---|
Formato: | Artículo |
Lenguaje: | English |
Publicado: |
Wiley
2012-01-01
|
Colección: | Advances in Hematology |
Acceso en línea: | http://dx.doi.org/10.1155/2012/627920 |