Regiospecific synthesis, antibacterial and anticoagulant activities of novel isoxazoline chromene derivatives

Regiospecific synthesis, antibacterial and anticoagulant activities of novel isoxazoline chromene derivatives

The synthesis and pharmacological evaluation of new series of 4-((3-aryl-4,5-dihydroisoxazol-5-yl)methoxy)-2H-chromen-2-ones 3a–f prepared by cycloaddition reaction using various arylnitrile oxides with the suitable 4-(allyloxy)-2H-chromen-2-one 2a are described. The 2-methyl-2,3-dihydrothieno[3,2-c...

Full description

Bibliographic Details
Main Authors: Imen Zghab, Belsem Trimeche, Mohamed Ben Mansour, Mohsen Hassine, David Touboul, Hichem Ben Jannet
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Arabian Journal of Chemistry
Subjects:
1,3-Dipolar cycloaddition
Allylic halides
Five-membered heterocyclic
Isoxazoline chromenes
Antibacterial activity
Anticoagulant activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535213003481

Internet

http://www.sciencedirect.com/science/article/pii/S1878535213003481

Similar Items