Longitudinal analysis of FcRL5 expression and clonal relationships among classical and atypical memory B cells following malaria

Longitudinal analysis of FcRL5 expression and clonal relationships among classical and atypical memory B cells following malaria

Abstract Background Chronic and frequently recurring infectious diseases, such as malaria, are associated with expanded populations of atypical memory B cells (MBCs). These cells are different from classical MBCs by the lack of surface markers CD21 and CD27 and increased expression of inhibitory rec...

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Bibliographic Details
Main Authors: S. Jake Gonzales, Sebastiaan Bol, Ashley E. Braddom, Richard Sullivan, Raphael A. Reyes, Isaac Ssewanyana, Erica Eggers, Bryan Greenhouse, Evelien M. Bunnik
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Adaptive immune response
Humoral immunity
B cell differentiation
Infection
BCR-sequencing
Online Access:https://doi.org/10.1186/s12936-021-03970-1

Internet

https://doi.org/10.1186/s12936-021-03970-1

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