Disease-dependent local IL-10 production ameliorates collagen induced arthritis in mice.

Rheumatoid arthritis (RA) is a chronic destructive autoimmune disease characterised by periods of flare and remission. Today's treatment is based on continuous immunosuppression irrespective of the patient's inflammatory status. When the disease is in remission the therapy is withdrawn but...

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Bibliographic Details
Main Authors: Louise Henningsson, Tove Eneljung, Pernilla Jirholt, Sara Tengvall, Ulf Lidberg, Wim B van den Berg, Fons A van de Loo, Inger Gjertsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3500327?pdf=render