Neuromelanin magnetic resonance imaging of substantia nigra and locus coeruleus in Parkinson’s disease with freezing of gait

Neuromelanin magnetic resonance imaging of substantia nigra and locus coeruleus in Parkinson’s disease with freezing of gait

BackgroundThe downregulation of monoamines, especially dopamine in substantia nigra (SN) and norepinephrine in locus coeruleus (LC), may be responsible for freezing of gait (FOG) pathological basis in Parkinson’s disease (PD).MethodsThirty-two Parkinson’s disease patients with freezing of gait (PD-F...

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Bibliographic Details
Main Authors: Shangpei Wang, Tong Wu, Yajie Cai, Yongqiang Yu, Xianwen Chen, Longsheng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson’s disease
freezing of gait
neuromelanin MRI
substantia nigra
locus coeruleus
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1060935/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1060935/full

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