Polygenic risk score predicts risk of primary sclerosing cholangitis in inflammatory bowel disease

Background Forty distinct primary sclerosing cholangitis (PSC) genomic loci have been identified through multiancestry meta-analyses. The polygenic risk score (PRS) could serve as a promising tool to discover unique disease behaviour, like PSC, underlying inflammatory bowel disease (IBD).Aim To test...

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Bibliographic Details
Main Authors: William A Faubion, Rodney D Newberry, Ming-Hsi Wang, Jessica J Friton, Laura E Raffals, Jonathan A Leighton, Shabana F Pasha, Michael F Picco, Kelly Monroe, Billy D Nix
Format: Article
Language:English
Published: BMJ Publishing Group 2023-11-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/10/1/e001141.full