Polygenic risk score predicts risk of primary sclerosing cholangitis in inflammatory bowel disease

Polygenic risk score predicts risk of primary sclerosing cholangitis in inflammatory bowel disease

Background Forty distinct primary sclerosing cholangitis (PSC) genomic loci have been identified through multiancestry meta-analyses. The polygenic risk score (PRS) could serve as a promising tool to discover unique disease behaviour, like PSC, underlying inflammatory bowel disease (IBD).Aim To test...

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Bibliographic Details
Main Authors: William A Faubion, Rodney D Newberry, Ming-Hsi Wang, Jessica J Friton, Laura E Raffals, Jonathan A Leighton, Shabana F Pasha, Michael F Picco, Kelly Monroe, Billy D Nix
Format: Article
Language:English
Published: BMJ Publishing Group 2023-11-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/10/1/e001141.full

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