Circulating and tumor-infiltrating myeloid-derived suppressor cells in patients with colorectal carcinoma.

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous family of myeloid cells that suppress T cell immunity in tumor-bearing hosts. In patients with colon cancer, MDSCs have recently been described as Lin(-/low)HLA-DR(-)CD11b(+)CD33(+) cells correlating with cancer stage, metastasis and chemo...

Full description

Bibliographic Details
Main Authors: Bin Zhang, Zhijun Wang, Liangliang Wu, Meng Zhang, Wei Li, Jianhua Ding, Jun Zhu, Huafeng Wei, Ke Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3577767?pdf=render