VEGFA, MYC, and JUN are abnormally elevated in the synovial tissue of patients with advanced osteoarthritis

Abstract Osteoarthritis (OA), affecting > 500 million people worldwide, profoundly affects the quality of life and ability to work. The mitogen-activated protein kinase (MAPK) signaling pathway plays an essential role in OA. To address the lack of studies focused on synovial cells in OA, we evalu...

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Detalhes bibliográficos
Principais autores: Genxiang Rong, Zhenyu Zhang, Wenjing Zhan, Minnan Chen, Jingjing Ruan, Cailiang Shen
Formato: Artigo
Idioma:English
Publicado em: Nature Portfolio 2025-01-01
coleção:Scientific Reports
Assuntos:
Acesso em linha:https://doi.org/10.1038/s41598-024-80551-7