Position of UNC-13 in the active zone regulates synaptic vesicle release probability and release kinetics
The presynaptic active zone proteins UNC-13/Munc13s are essential for synaptic vesicle (SV) exocytosis by directly interacting with SV fusion apparatus. An open question is how their association with active zones, hence their position to Ca2+ entry sites, regulates SV release. The N-termini of major...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2013-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/01180 |