Clarifying the biological and statistical assumptions of cross-sectional biological age predictors: an elaborate illustration using synthetic and real data

Abstract Background There is divergence in the rate at which people age. The concept of biological age is postulated to capture this variability, and hence to better represent an individual’s true global physiological state than chronological age. Biological age predictors are often generated based...

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Bibliographic Details
Main Authors: Marije H. Sluiskes, Jelle J. Goeman, Marian Beekman, P. Eline Slagboom, Hein Putter, Mar Rodríguez-Girondo
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-024-02181-x