IL-22BP production is heterogeneously distributed in Crohn’s disease

IL-22BP production is heterogeneously distributed in Crohn’s disease

Crohn’s disease (CD), a form of inflammatory bowel disease (IBD), is characterized by impaired epithelial barrier functions and dysregulated mucosal immune responses. IL-22 binding protein (IL-22BP) is a soluble inhibitor regulating IL-22 bioactivity, a cytokine proposed to play protective roles dur...

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Bibliographic Details
Main Authors: Aurélie Fantou, Eric Lagrue, Thomas Laurent, Laurence Delbos, Stéphanie Blandin, Anne Jarry, Gaëlle Beriou, Cécile Braudeau, Nina Salabert, Eros Marin, Aurélie Moreau, Juliette Podevin, Arnaud Bourreille, Régis Josien, Jérôme C. Martin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
IL-22BP
IL-22
Crohn’s disease
mononuclear phagocytes
eosinophils
disease location
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1034570/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1034570/full

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