Creatine Kinase Equilibration and ΔG<sub>ATP</sub> over an Extended Range of Physiological Conditions: Implications for Cellular Energetics, Signaling, and Muscle Performance

Creatine Kinase Equilibration and ΔG<sub>ATP</sub> over an Extended Range of Physiological Conditions: Implications for Cellular Energetics, Signaling, and Muscle Performance

In this report, we establish a straightforward method for estimating the equilibrium constant for the creatine kinase reaction (CK K<sub>eq</sub>″) over wide but physiologically and experimentally relevant ranges of pH, Mg<sup>2+</sup> and temperature. Our empirical formula f...

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Bibliographic Details
Main Authors: Robert Woodbury Wiseman, Caleb Micah Brown, Thomas Wesley Beck, Jeffrey John Brault, Tyler Robert Reinoso, Yun Shi, Prescott Bryant Chase
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
skeletal muscle
actomyosin ATPase
ADP
temperature
cytoplasmic magnesium ion concentration
cytoplasmic pH
Online Access:https://www.mdpi.com/1422-0067/24/17/13244

Internet

https://www.mdpi.com/1422-0067/24/17/13244

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