Wild-Type and Mutant FUS Expression Reduce Proliferation and Neuronal Differentiation Properties of Neural Stem Progenitor Cells

Wild-Type and Mutant FUS Expression Reduce Proliferation and Neuronal Differentiation Properties of Neural Stem Progenitor Cells

Nervous system development involves proliferation and cell specification of progenitor cells into neurons and glial cells. Unveiling how this complex process is orchestrated under physiological conditions and deciphering the molecular and cellular changes leading to neurological diseases is mandator...

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Bibliographic Details
Main Authors: Eleonora Stronati, Stefano Biagioni, Mario Fiore, Mauro Giorgi, Giancarlo Poiana, Camilla Toselli, Emanuele Cacci
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
Fused in Sarcoma/Translocated in Liposarcoma (FUS/TLS)
cell proliferation
cell differentiation
neural stem progenitor cells (NSPC)
ALS
FUS-linked disease
Online Access:https://www.mdpi.com/1422-0067/22/14/7566

Internet

https://www.mdpi.com/1422-0067/22/14/7566

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