Ensemble-Level Organization of Human Kinetochores and Evidence for Distinct Tension and Attachment Sensors

Ensemble-Level Organization of Human Kinetochores and Evidence for Distinct Tension and Attachment Sensors

Summary: Kinetochores are multi-protein machines that form dynamic attachments to microtubules and control chromosome segregation. High fidelity is ensured because kinetochores can monitor attachment status and tension, using this information to activate checkpoints and error-correction mechanisms....

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Bibliographic Details
Main Authors: Emanuele Roscioli, Tsvetelina E. Germanova, Christopher A. Smith, Peter A. Embacher, Muriel Erent, Amelia I. Thompson, Nigel J. Burroughs, Andrew D. McAinsh
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720304356

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http://www.sciencedirect.com/science/article/pii/S2211124720304356

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